Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p249 | Genetics and Epigenetics | ECTS2016

Identification of epigenomic regulators of osteoblast function

Henaff Carole Le , Partridge Nicola , Jehan Frederic , Geoffroy Valerie

Molecularly characterized epigenetic networks that control bone formation and are altered during aging are necessary to uncover new potential targets for osteoanabolic therapy. Our contribution to the iBONE consortium is to identify osteoanabolic epigenomic regulators by screening which are involved in osteoblast phenotype and differentiation. This study will be done by a 3 step approach including: siRNA screening for epigenomic regulators of osteoblastic differentiation and v...